LUCIA Metaphase Finder Improves Your...
... Reliability
The Metaphase Finder system consists of carefully selected top quality hardware components all produced by well-established manufacturers. In a very compact setup, you can find the following devices cooperating together:
- Nikon Eclipse 90i microscope - The computer controlled illumination ensures stable light conditions. The absolute coordinates focus control ensures reliable and fast auto focus.
- Jenoptik ProgRes MF camera - A highly sensitive camera which brings the top image quality and more than sufficient speed.
- Prior PL-200 Slide Loader, ProScan motorized stage - These two devices compose a highperformance combination providing precision, speed and reliability of scanning.
... Flexibility
- The loader with the capacity of 200 slides together with the integrated bar code reader open ways to build a highly effective system.
- A training-capable metaphase classifier can be fine-tuned to handle different sample types and preparation techniques.
- Thanks to the network-based database and full bar code support, the system is broadly extensible and can whenever be adapted to meet increasing demands.
... Comfort
- Press one button - Once the system is adjusted by the administrator, the scanning process can be run by a single button.
- Walk away - The slide loader capacity of 200 slides allows more then 24 hours of unattended scanning at approximate speed of 8 minutes per full slide (~90mm2).
- Check on the progress anytime - The scanning results are immediately accessible within the database
- Reload slides anytime - The scanned cassetes can be easily removed from the loader or changed during the scanning.
... Performance
- The network-accessible database provides fast access to the metaphase galleries including the stage coordinates data.
- Metaphases can be located and reviewed on any workstation thanks to the automatic coordinates recalculation procedure.
... Workflow
A perfect workflow may look like this:
- A thin database client PC allows registering new slides, associating them with patients in a database. After the preparation is done, the slides are placed into the loader cassettes.
- Metaphase Finder scans the slides and saves the metaphase thumbnails, associated with the patient according to the bar-code, into the database.
- Karyotyping workstations equipped with a handheld bar code scanner perform fast metaphase gallery look up, full-resolution image acquisition and analysis.


